Erbb2 does not have a known ligand. 随着对 erbb2 信号通路的深入研究以及新型靶向治疗药物的不断开发，针对 erbb2 阳性肿瘤的治疗策略将不断完善，有望为患者带来更多的治疗选择和更好的预后改善。 Studies have revealed that amplification or.
Arizona Traveler Information System (AZ511) Department of Transportation
Erbb2 缺乏已知的配体，但最近的结构研究表明其结构类似于配体激活状态并倾向于二聚化。 erbb 受体信号通过 akt、mapk 以及其他多种通路来调节细胞增殖、迁移、分化、. Function, proteins, disorders, pathways, orthologs, and. But erbb2 is the best candidate for the formation of a heterodimer with the other three receptors.
