Order now for fast global shipping and technical support. These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from. Bv6 is a small molecule inhibitor of inhibitor of apoptosis proteins (iaps), a family of proteins that play a key role in regulating cell death.
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Iaps are overexpressed in many types of cancer, and they. Bv6 inhibits the cell viability of hcc193 nsclc cells with ic50 of 7.2 μm, induces apoptosis in both hcc193 and h460 cell lines, and also significantly enhances the radiosensitivity of these cell lines. Bv6 acts as a smac mimetic.