Orphanet is part of the gene. The klln gene provides instructions for making a protein called killin. Klln, encoding klln protein, is a newly identified gene, which shares a bidirectional promoter with pten and is transcribed in the opposite direction.
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Official gene symbol, which is typically a short form of the gene name, according to hgnc. Klln is a transcription factor directly regulating ar, tp53, and tp73 expression, with a role in prostate carcinogenesis. Learn about this gene and related health conditions.
The expression of this dna.
Here, we report on klln’s role in dna damage response (ddr) mediated through apoptosis in breast cells with and without a cancer phenotype. So far, the function of klln has never. Pathogenic mutations in klln are rare in breast cancer. Global variome shared lovd the klln gene homepage.
Diseases associated with klln include cowden syndrome 4 and cowden syndrome. Active transcripts please note that a short description of a certain column can be displayed when you move your mouse cursor. Klln (killin, p53 regulated dna replication inhibitor) is a protein coding gene. The protein encoded by this intronless gene is found in the nucleus, where it can inhibit dna synthesis and promote s phase arrest coupled to apoptosis.
Klln expression was upregulated after.
The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment. He, x., yu, q., eng, c. Assigned hpa protein class (es) for the encoded protein (s).
